化身博士和鲨鱼先生

After losing his wife, the deranged and reclusive Dr. Henry Jekyll descends into a nightmare of grief and obsession - until he takes Sharcopine, an untested drug that warps his body into a bloodthirsty man-shark. Now driven by madness and love beyond the grave, Jekyll prowls the streets, hunting anyone who threatens his twisted relationship with his long-dead bride.

《化身博士和鲨鱼先生》的基础信息更偏电影，简介里的“After losing his wife, the derange...”提供了第一层判断，剩下可以再看主创和年代。